Topically Applied Immunotherapy for Pets

One gentle cream. Two reasons to believe in it.

Allibre is a once-daily, custom-formulated transdermal cream that calms canine and feline allergies. It was developed with board-certified veterinary dermatologists and evaluated in a clinical pilot study.

68% reduction in IgE levels observed in pilot study, with significant improvement in CADESI-4: see the clinical data →
For Veterinarians

Give clients a non-invasive option their pets will tolerate, helping improve compliance and treatment success.

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For Pet Owners

No injections. No pills. Just one gentle cream, applied to the ear once a day. Ask your veterinarian if it’s right for your pet.

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Identify & Relieve

Does This Sound Like Your Pet?

Common signs of environmental, food, and flea-related allergies in cats and dogs.

Itching & Scratching

Excessive itching and scratching is one of the most common signs of allergies in dogs and cats, often triggered by environmental or food factors.

Licking of Paws

Frequent paw licking is often a sign of irritation that your pet is trying to relieve on their own.

Red & Inflamed Skin

Redness or inflammation of the skin, often accompanied by itching, is a common allergic response.

Loss of Hair

Hair loss can result from excessive scratching and licking of an affected, irritated area.

Head Shaking & Ear Infections

Head shaking and recurring ear infections are especially common allergy symptoms in dogs.

Excessive Grooming

Excessive grooming is often an attempt to relieve discomfort, sometimes leading to further irritation.

A calm, healthy golden retriever outdoors
Real Relief

A Gentler Way to Manage Allergies

No wrestling with pills. No injections. Just a calm daily routine that fits into life with your pet, not against it.

  • Needle-free, once-daily application that fits naturally into your routine
  • Gentle enough for pets who fight pills or fear injections
  • Works toward lasting tolerance, not just masking symptoms
Our Technology

How It Works

A gradual, once-daily introduction of allergens, building to a personalized maintenance dose.

STEP 1
Visit Your Veterinarian

Speak with your veterinarian to see if Allibre could help your pet.

STEP 2
Allergy Testing

Your veterinarian assesses your pet for specific allergen sensitivities.

STEP 3
Submit Order

Your veterinarian submits your pet’s individualized allergy profile to Allibre.

STEP 4
Custom Preparation

Allibre prepares a treatment set specific to your pet’s unique allergy profile.

STEP 5
Begin Daily Use

Your treatment ships to your vet’s office, and you apply once daily to relieve symptoms.

Real Results

Trusted by Veterinarians. Loved by Pet Owners.

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68%
Reduction in IgE levels, plus significant CADESI-4 improvement
Observed in a veterinary dermatologist-led pilot study. See the clinical data →
Frequent Questions

Popular Questions About Treating Allergies in Dogs & Cats

What pet owners and veterinarians most often ask about Allibre™ and transdermal immunotherapy.

Transdermal immunotherapy delivers a pet’s specific allergens through the skin rather than by injection or oral drops, gradually building the immune system’s tolerance to those allergens over time. Allibre applies this as a once-daily cream to the inner ear pinna. It's the same immunotherapy goal as allergy shots or sublingual drops, just without needles, clinic visits, or precise daily dosing schedules.

Both. Allibre is custom-formulated for each patient based on an allergy-profile workup, and is used to manage environmental allergies (atopic dermatitis) in canine and feline patients alike.

No. Allibre is an immunotherapy, not a steroid, antihistamine, or itch-suppressing drug. Rather than masking the itch response, it aims to gradually build the immune system’s tolerance to a pet’s specific allergens. That's the same underlying goal as injectable or sublingual allergen immunotherapy, delivered differently.

Cytopoint (lokivetmab) is an injectable monoclonal antibody that relieves itching by blocking a specific itch signal. That's a different drug class and mechanism entirely. Allibre is an allergen immunotherapy that targets the underlying immune response to a pet’s specific allergens rather than suppressing the itch signal. See our full Allibre vs. Cytopoint comparison for detail.

No. Allibre is available to be ordered by veterinarians only, following an allergy-profile workup and an established veterinarian-client-patient relationship. If you think Allibre might be right for your pet, talk to your veterinarian.

In a pilot study conducted with board-certified veterinary dermatologists, treated canines showed a 68% reduction in D. farinae-specific IgE, along with significant improvement in CADESI-4 (Canine Atopic Dermatitis Extent and Severity Index) scores. See the Clinical Data page for full results and source documents.

Response time varies by pet and allergy severity, but some pets show improvement in as little as 4 weeks of consistent daily application. Allibre follows an induction phase that gradually increases allergen concentration over the first several months, followed by an ongoing once-daily maintenance dose.